Generally oral drug delivery systems do distribute the drug with no exacting release pattern and reach the targeted system with less control effective concentration subsequently random plasma concentration. To overcome this difficulty a lot of study and improvement had done, which has involved into NDDS i.e. novel drug delivery system. It’s a huge system dealing with different release pattern like matrix, diffusion, osmotic floating liposome, nano particles, microsphere etc. These days aged as well as innovative disease treatments utilize presently developed systems for its avoidance and heal which includes NDDS which is beneficiary for patients. In NDDS, among all, osmotic drug delivery system is presently trendy in market because of its some qualities over other delivery systems. In this review article collection of old to latest technologies of osmotic delivery systems has been incorporated. Osmotic system is based on osmosis and osmotic pressure which is driving force for the solvent to pass through semi permeable membrane until equilibrium occur between the two compartments i.e. internal and external. It mostly consists of three things-a semi permeable membrane, a core and a delivery orifice.
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